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Crystallographic and Modeling Methods in Molecular Design download ebook

by Charles E. Bugg,Steven E. Ealick

Crystallographic and Modeling Methods in Molecular Design download ebook
ISBN:
0387972102
ISBN13:
978-0387972107
Author:
Charles E. Bugg,Steven E. Ealick
Publisher:
Springer; 1990 edition (July 23, 1990)
Language:
Pages:
269 pages
ePUB:
1663 kb
Fb2:
1847 kb
Other formats:
doc mobi azw lit
Category:
Medicine & Health Sciences
Subcategory:
Rating:
4.9

This book contains the papers that were presented at the "Crystallo­ graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989

eBook 53,54 €. price for Russian Federation (gross). This book contains the papers that were presented at the "Crystallo­ graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989. During the past few years, there has been a burst of activity in this area, especially related to drug design and protein engineering projects.

This book contains the papers that were presented at the "Crystallo­ graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989.

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Crystallographic and Modeling Methods in Molecular Design. Charles E. Bugg, Steven E. Ealick

Crystallographic and Modeling Methods in Molecular Design. Ealick.

New Biological Books. Crystallographic and Modeling Methods in Molecular Design. Based on a Symposium Held in Gulf Shores, Alabama, April 30-May 3, 1989.

book This book contains the papers that were presented at the "Crystallo- graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989.

This book contains the papers that were presented at the "Crystallo- graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989.

Read instantly in your browser. ISBN-13: 978-1461279877. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30. Qty:1. has been added to your Cart.

Jul 8, 1991 - molecular graphics and semiquantitative evaluation of the interaction energies between the . Biophysics: Ealick et al. HNlN.

Jul 8, 1991 - molecular graphics and semiquantitative evaluation of the interaction energies between the inhibitors and the enzyme aided in prioritization for. The concept of drug design based on crystallographic and modeling methods has received much attention, yet few solid examples have appeared in the literature.

TA Jones, M Bergdoll, M Kjeldgaard. New York: Springer-Verlag, 1990. HIV-1 nucleocapsid protein zinc finger structures induce tRNALys, 3 structural changes but are not critical for primer/template annealing. MRS Hargittai, AT Mangla, RJ Gorelick, K Musier-Forsyth. Journal of molecular biology 312 (5), 985-997, 2001.

Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors. SE Ealick, YS Babu, CE Bugg, MD Erion, WC Guida, JA Montgomery,. Proceedings of the National Academy of Sciences 88 (24), 11540-11544, 1991. The crystal structure and mechanism of orotidine 5′-monophosphate decarboxylase. TC Appleby, C Kinsland, TP Begley, SE Ealick. Proceedings of the National Academy of Sciences 97 (5), 2005-2010, 2000.

This book contains the papers that were presented at the "Crystallo­ graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989. During the past few years, there has been a burst of activity in this area, especially related to drug design and protein engineering projects. The purpose of the symposium and this book is to provide an up-to­ date review of the most recent experimental and theoretical approaches that are being used for molecular design. The book covers several re­ cent examples of approaches for using crystallography in conjunction with forefront modeling methods for guiding the development of en­ zyme inhibitors and of peptides and proteins with modified biological and physical properties. In addition, this book contains discussions of new approaches for combining crystallographic data and advanced computational techniques for aiding in the design of enzyme inhibitors and other compounds that bind to selected biological targets. This book is therefore of interest not only to molecular biologists and biochem­ ists, but is stimulating reading for anyone involved in structural biol­ ogy, pharmaceutical chemistry, enzymology, protein engineering, and biotechnology. The meeting was the third in a series of symposia initiated and spon­ sored by the Department of Biochemistry, University of Alabama at Birmingham.