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Junk DNA: A Journey Through the Dark Matter of the Genome download ebook

by Nessa Carey

Junk DNA: A Journey Through the Dark Matter of the Genome download ebook
ISBN:
023117084X
ISBN13:
978-0231170840
Author:
Nessa Carey
Publisher:
Columbia University Press (April 14, 2015)
Language:
Pages:
360 pages
ePUB:
1394 kb
Fb2:
1186 kb
Other formats:
rtf mobi doc txt
Category:
Biological Sciences
Subcategory:
Rating:
4.5

Junk DNA was originally defined as DNA that does not code for proteins (and this is the definition that Dr. Carey uses). According to that definition, 98% of human DNA is Junk and, indeed, was at one time thought to have no function

Junk DNA was originally defined as DNA that does not code for proteins (and this is the definition that Dr. According to that definition, 98% of human DNA is Junk and, indeed, was at one time thought to have no function. However, for some time, hints have been showing up in the scientific literature for the general reader that at least some Junk DNA is functional.

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From the author of the acclaimed The Epigenetics Revolution ('A book that. Goodreads helps you keep track of books you want to read. Start by marking Junk DNA: A Journey Through the Dark Matter of the Genome as Want to Read: Want to Read savin. ant to Read.

Conor Carey, Finn Carey and Gabriel Carey all played a role in this . This definition will evolve through the course of the book. 1. Why Dark Matter Matters. Sometimes life seems to be cruel in the troubles it piles onto a family. Consider this example.

Conor Carey, Finn Carey and Gabriel Carey all played a role in this, and outside the genetic clan I’d also like to thank Iona Thomas-Wright. Endless support and lots of biscuits have been provided by my ever-patient, delightful mother-in-law, Lisa Doran. After my first book The Epigenetics Revolution was published, I realised the readership was quite binary with respect to gene names. Some people love knowing which gene is being discussed, but for other readers it disrupts the flow horribly.

Sandero probably has a good claim to this honour, at about 1 per cent of the cost of the Veyron. But both cars have a number of things in common, and one of these is that each needs to be switched on before you can go anywhere. If you don’t activate the engine systems, nothing will happen. Our protein-coding genes are the same

Junk DNA. Book Description: For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins.

Junk DNA. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose.

From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science

Read unlimited books and audiobooks on the web, iPad, iPhone and Android. From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’.

2 Junk DNA: A Journey Through the Dark Matter of the Genome. Epigenetics for Drug Discovery. Carey's books and lectures explain developments in epigenetics to a scientifically interested general audience

2 Junk DNA: A Journey Through the Dark Matter of the Genome. Education and career. Carey attended state schools. She first attended the University of Edinburgh to study veterinary medicine. Carey's books and lectures explain developments in epigenetics to a scientifically interested general audience.

Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to. .

Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word "gene" and has engendered a bitter battle over whether or not this genomic "nonsense" is the source of human biological complexity. We are only now unlocking the secrets of junk DNA, and Carey's book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field.

Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. Nessa Carey has a PhD in virology from the University of Edinburgh and worked in the biotech and pharma industry for thirteen years. She is a Visiting Professor at Imperial College, London. Her previous book, The Epigenetics Revolution, was published by Icon Books in 2011. and described as a 'book that would have had Darwin swooning – anyone seriously interested in who we are and how we function should read this.

Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes . These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field. Columbia University Press.

For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions.Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field.
Reviews:
  • Black_Hawk_Down
If you love following the latest discoveries in the world of genetics, this book will serve as a great introduction to the "dizzying" world of "Junk DNA", the non-protein-coding regions of the human genome. The book doesn't shy away from the complexity but is written in a way that those who love biology can follow.
  • Funny duck
A well written overview, essential for anyone interested in the biological sciences.
  • Fohuginn
Too technical for what I expected.
  • Malodora
This book is mostly repeating what “ the epigenetic revolution” says, i must admit after reading the first one, i could not go very far in this one. Both require a good taste for strong science, as it is solid evidence-based facts. But epigenetics is a fantastic tool that Nature (God? The Source? The Univers?) gave us to reinvent, reshape, redefine ourselfs, through 95% of our DNA, so we can change how the 5% left are expressed, like you change the decoration of a Xmas tree until it FEELS good. Yes we can. That’s in our reach...that the power of mind over matter. Rejoice and DO IT.
  • Yar
Bye bye selfish DNA and the era of hard-working "junk" DNA. Dawkins, like Hoyle, will regret his naming.
  • SlingFire
This is Nessa Carey’s second book and, like her first (The Epigenetics Revolution), it leads the reader into scientific territory that is unfamiliar: As far as I know, this is the first book for the non-specialist reader on Junk DNA. Also like her first book, it is a model for the careful presentation of complex details.

Junk DNA was originally defined as DNA that does not code for proteins (and this is the definition that Dr. Carey uses). According to that definition, 98% of human DNA is Junk and, indeed, was at one time thought to have no function. However, for some time, hints have been showing up in the scientific literature for the general reader that at least some Junk DNA is functional. In this book, Dr. Carey, presents a detailed account of what we know at present about the function of Junk DNA and its consequences. Most of her discussion is built around cases in which mutations in Junk DNA have occurred (or been inherited) resulting in severe medical conditions. She illustrates her often complex examples with simple analogies and helpful diagrams. I cannot say that I followed all of them the first time through but I am confident that, with more application on my part, I would be able to do so.

These are relatively early days in the field of Junk DNA: It is not yet known how much carries a function and how much does not. However, Dr. Carey’s book makes it clear that, although not coding for proteins, much of our Junk DNA does perform a large variety of complex and critically important functions. Indeed, it may be that it is responsible for the complexity of Homo sapiens and other contemporary species.
  • Lilegha
Despite being a student of genetics, this tomb was eye opening! Recommended highly!
Using very clear presentation, including apt analogies, Nessa Carey makes quite complex material easier to understand.